中国普外基础与临床杂志

中国普外基础与临床杂志

碳纳米材料在胃癌治疗中的应用进展

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目的 了解碳纳米材料在胃癌治疗中的应用现状。 方法 对国内外有关碳纳米材料应用于胃癌治疗中的文献进行复习并进行综述。 结果 碳纳米材料作为淋巴结示踪剂在胃癌淋巴结中染色明显,示踪效果好,能够提高淋巴结的检出数量及淋巴结转移阳性率。碳纳米材料作为化疗药物载体,可以提高淋巴结内药物的浓度从而抑制胃癌细胞的转移。 结论 碳纳米材料能够为胃癌的治疗提供有效帮助,但其是否能改善胃癌的预后仍有待研究。

Objective To summarize application status of carbon nanomaterials in gastric cancer therapy. Method The relevant literatures about the application of the carbon nanomaterials in the gastric cancer were reviewed. Results The carbon nanomaterials was as a lymph tracer with good effects for dying and tracing, which could improve the detection rate of lymph nodes and the positive rate of metastasis lymph nodes. As be made as a transition of chemotherapy drugs, the carbon nanomaterials could improve the concentration of the drug in the lymph node, then inhibit the gastric cancer cell to spread. Conclusion Carbon nanomaterial provides an effective help in treatment for gastric cancer, but whether it could improve prognosis of patient with gastric cancer remains to be studied.

关键词: 碳纳米材料; 胃癌; 治疗; 进展

Key words: carbon nanoparticle; gastric cancer; treatment; progress

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