中国普外基础与临床杂志

中国普外基础与临床杂志

胃肝样腺癌的 MDT 讨论

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目的 讨论胃肝样腺癌的临床表现、诊断和治疗。 方法 对四川大学华西医院于 2017 年 10 月收治的 1 例胃肝样腺癌患者在术前所进行的 MDT(multi-disciplinary team)讨论进行总结,并复习文献,分析胃肝样腺癌的临床病理学特点。 结果 胃肝样腺癌的临床特点是常伴有早期肝转移和甲胎蛋白(AFP)明显升高,易误诊为原发性肝细胞癌。其病理组织学特点是,形态上具有肝癌样分化和腺癌样分化两种结构。 结论 胃肝样腺癌是胃腺癌的特殊类型,根治性手术是其主要治疗手段,但预后较差。

Objective To discuss the clinical manifestations, diagnosis, and treatment of hepatoid adenocarcinoma of the stomach. Methods By summarizing the multi-disciplinary team results of 1 patient with hepatoid adenocarcinoma of the stomach, who underwent surgery in West China Hospital in October 2017, as well as reviewing the related literatures, to explore the clinicopathological features of hepatoid adenocarcinoma of the stomach. Results The clinical features of hepatoid adenocarcinoma of the stomach were often accompanied by early liver metastasis and alpha fetoprotein (AFP) significantly increased, which were easily misdiagnosed as primary hepatocellular carcinoma. The histopathological features of hepatoid adenocarcinoma of the stomach were characterized by two structures: hepatocellular carcinoma and adenocarcinoma. Conclusion Hepatoid adenocarcinoma of the stomach is a special type of gastric adenocarcinoma, and radical operation is the main treatment, but the prognosis of it is poor.

关键词: 胃肝样腺癌; 原发性肝细胞癌; 甲胎蛋白; MDT

Key words: hepatoid adenocarcinoma of the stomach; primary hepatocelluar carcinoma; alpha fetoprotein; multi-disciplinary team

引用本文: 苏伟, 张胜龙, 王文涛, 陈卫霞, 鲁昌立, 彭星辰. 胃肝样腺癌的 MDT 讨论. 中国普外基础与临床杂志, 2018, 25(2): 213-220. doi: 10.7507/1007-9424.201712015 复制

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