中国普外基础与临床杂志

中国普外基础与临床杂志

原发性结直肠印戒细胞癌的研究进展

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目的 总结原发性结直肠印戒细胞癌的研究进展。 方法 检索近年来国内外有关结直肠印戒细胞癌的相关文献,对其研究进展作一综述。 结果 结直肠印戒细胞癌是结直肠腺癌的一种病理学亚型,发病率极低,但恶性程度高、预后差。在仔细查阅了相关文献后本文从流行病学、分子机制、临床病理、预后及治疗等方面对其进行了详细地介绍。 结论 虽然我们对结直肠印戒细胞癌已经有了一定程度的了解,但由于较多相关文献的样本较小,或为单中心研究,因而研究结果存在局限,故未来仍需更多的研究来提高对结直肠印戒细胞癌的认知。

Objective To summarize the current research advances of colorectal signet-ring cell carcinoma (SRCC). Methods In this paper, the related literatures of colorectal SRCC in recent years were reviewed. Results Colorectal SRCC was a pathological subtype of colorectal adenocarcinoma, with extremely low incidence but high malignancy and poor prognosis. After reviewing the relevant research carefully, this article introduced the epidemiology, molecular mechanism, clinicopathology, prognosis and treatment of colorectal SRCC in detail. Conclusion Although we already have a certain degree of understanding about colorectal SRCC, due to the limitations in the results of some related researches because of the small sample size or the single-center study, we still need more researches to improve the cognition of colorectal SRCC.

关键词: 结直肠印戒细胞癌; 研究进展; 综述

Key words: colorectal signet-ring cell carcinoma; research advance; review

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